Characterization of gene expression induced by RTN-1C in human neuroblastoma cells and in mouse brain
The endoplasmic reticulum (ER) stress-mediated pathway is involved in a wide range of human neurodegenerative disorders.Hence, molecules that regulate the ER stress response represent potential candidates as drug targets to tackle these diseases.In previous studies we demonstrated that upon acetylation the reticulon-1C (RTN-1C) variant of the retic